Disruption of Sleep Microarchitecture Is a Sensitive and Early Marker of Parkinson's Disease.

Christopher E J Doppler, Julia Smit,Maximilian Hommelsen,Aline Seger,Niels Okkels,Jacob Horsager,Martin Kinnerup,Allan K Hansen,Tatyana D Fedorova,Karoline Knudsen,Marit Otto,Adjmal Nahimi,Gereon R Fink,Per Borghammer,Michael Sommerauer

Journal of Parkinson's Disease（2022）

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摘要

Data suggest that alterations of sleep microarchitecture are an early and more sensitive characteristic of Parkinson's disease than changes in sleep macroarchitecture.

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关键词

Parkinson’s disease,REM sleep behavior disorder,cyclic alternating pattern,microsleep,polysomnography

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