GBP5 Inhibition Ameliorates the Progression of Lupus Nephritis by Suppressing NLRP3 Inflammasome Activation.
Immunological investigations(2023)
摘要
Our findings reveal that GBP5 inhibition prevents the progression of LN, most likely by suppressing NLRP3 inflammasome activation. It provides a novel insight into the therapeutic interventions for LN.
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关键词
Guanylate-binding protein 5,NLRP3 inflammasome,inflammation,lupus nephritis
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