GBP5 Inhibition Ameliorates the Progression of Lupus Nephritis by Suppressing NLRP3 Inflammasome Activation.

Immunological investigations(2023)

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摘要
Our findings reveal that GBP5 inhibition prevents the progression of LN, most likely by suppressing NLRP3 inflammasome activation. It provides a novel insight into the therapeutic interventions for LN.
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关键词
Guanylate-binding protein 5,NLRP3 inflammasome,inflammation,lupus nephritis
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