Leflunomide-induced and paraneoplastic ulcers in a rheumatoid arthritis patient

Michael R. Vittori, Jonathan Z. Tang,William H. McCoy

JAAD Case Reports（2022）

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摘要

Patients with rheumatoid arthritis (RA) are predisposed to ulcer formation because of their primary disease process, treatment regimens, and comorbid conditions.1 Recently, ulceration in RA patients has been linked to both an RA treatment (leflunomide)2-5 and a rare malignancy associated with RA (large granular lymphocytic [LGL] leukemia).6

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关键词

large granular lymphocytic leukemia,leflunomide,paraneoplastic,pyoderma gangrenosum,rheumatoid arthritis,ulcer

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