miR-31/QKI-5 axis facilitates cell cycle progression of non-small-cell lung cancer cells by interacting and regulating p21 and CDK4/6 expressions.

Cancer medicine(2023)

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摘要
Our results suggest that the miR-31/QKI-5/p21-CDK4-CDK6 axis might have critical functions in the progression of NSCLC, and targeting this axis could serve as a potential therapeutic strategy for NSCLC.
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关键词
CDK4/6,MicroRNA-31,P21,QKI-5,cell cycle,non-small-cell lung cancer
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