Loss of p16 expression is a risk factor for recurrence in sinonasal inverted papilloma.

M Menendez,V N Cabal,B Vivanco, L Suarez-Fernandez,F Lopez, J L Llorente,M A Hermsen, C Alvarez-Marcos

RHINOLOGY（2022）

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摘要

HPV infection appears to play a minor role in SNIP and SNSCC and p16 immunostaining does not appear a valid surrogate marker for HPV. However, reduced or loss p16 expression may have prognostic value as a risk marker for recurrent SNIP.

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关键词

sinonasal inverted papilloma,sinonasal squamous cell carcinoma,recurrence,HPV,p16

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