Functional role of CD40 and CD154 costimulatory signals in IgZ-mediated immunity against bacterial infection

Ning Su,Chong-bin Hu,Tong Shao,Chun-yu Jin,Hao Li,Jian-fei Ji,Lu-lu Qin,Dong-Dong Fan,Ai-fu Lin,Li-xin Xiang,Jian-zhong Shao

Fish and Shellfish Immunology Reports（2021）

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摘要

•Regulatory role of Cd40 and Cd154 in IgZ-mediated antibacterial defense.•Differential role of Cd40-Cd154 interaction in bacterial TD and TI antigen-induced IgZ immunity.•Insights into the coevolution between IgZ/IgT immunoglobins and CD40/CD154 costimulatory molecules.

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关键词

CD40,CD154,IgZ,Costimulatory regulation,Antibacterial immunity

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