Risk Factors for Colistin-Resistant Carbapenem-Resistant Klebsiella pneumoniae in the Postacute Care Setting

Helen L Zhang,Jennifer H Han,Zena Lapp,Evan Snitkin,Ellie J C Goldstein,Sean Muldoon,Pam Tolomeo,Ebbing Lautenbach

OPEN FORUM INFECTIOUS DISEASES（2022）

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摘要

We assessed risk factors for colistin resistance among carbapenem-resistant Klebsiella pneumoniae (CRKP) from 375 patients in long-term acute care hospitals. Recent colistin or polymyxin B exposure was associated with increased odds of colistin resistance (adjusted odds ratio=1.11 per day of exposure, 95% confidence interval = 1.03-1.19, P=.007).

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carbapenem-resistant Klebsiella pneumoniae, colistin, long-term acute care hospitals

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