Biochemical Characterization of a Cyanobactin Arginine-N-Prenylase from the Autumnalamide Biosynthetic Pathway

Claudia Clemente, Nicholas Johnson,Xiaodan Ouyang,Rafael Popin,Sergio Dall'Angelo,Matti Wahlsten,Jouni Jokela,Alessandro Colombano, Brunello Nardone,David Fewer,Wael Houssen

Chemical Communications（2022）

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摘要

Cyanobactins are linear and cyclic post-translationally modified peptides. Here we show that the prenyl-D-Arg-containing autumnalamide A is a member of the cyanobactin family. Biochemical assays demonstate that the AutF prenyltransferase...

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biosynthetic pathway,biochemical characterization,autumnalamide

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