Differential impact of PI3K/AKT/mTOR signaling on tumor initiation and progression in animal models of prostate cancer.

Shuaibin Wang,Chao Zhang,Zhifang Xu,Michael H Chen, Haiyan Yu,Lizhong Wang,Runhua Liu

The Prostate（2023）

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摘要

Our results for genetically engineered mouse models suggest a differential role of the PI3K/AKT/mTOR signaling nodes in prostate cancer initiation and progression, but the underlying molecular mechanisms remain unaddressed.

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关键词

AKT,PTEN,TSC1,TSC2,prostate cancer

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