Factor IX inhibitors in haemophilia B: A report of National Haemophilia Registry in China.

Xueqing Dou,Wenhui Zhang,Man-Chiu Poon,Xinsheng Zhang,Runhui Wu,Xiaoqin Feng,Linhua Yang,Peng Cheng, Shu Chen, Ying Wang,Hu Zhou,Meijuan Huang,Yanping Song,Chenghao Jin,Donglei Zhang,Lingling Chen,Wei Liu,Lei Zhang,Feng Xue,Renchi Yang

Haemophilia : the official journal of the World Federation of Hemophilia（2023）

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摘要

This study reports the largest Chinese cohort of HB inhibitor patients. Large deletions were most significantly associated with inhibitor development. Low-dose ITI might be feasible for FIX inhibitor eradication.

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关键词

China,F9 gene mutation,anaphylaxis,haemophilia B,immune tolerance induction,inhibitor

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