Unveiling interaction mechanisms between myricitrin and human serum albumin: Insights from multi-spectroscopic, molecular docking and molecular dynamic simulation analyses

Tianmei Niu,Xiaojing Zhu,Dongsheng Zhao,Huifen Li,Peizheng Yan, Lulu Zhao, Wenguang Zhang,Pan Zhao,Beibei Mao

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy（2023）

引用 13|浏览4

暂无评分

摘要

•The interaction between myricitrin and human serum albumin has been firstly investigated.•Quenching mechanism, binding constants, thermodynamic parameters, and binding modes were discussed and mutually confirmed.•Myricitrin spontaneously binds to HSA site I, and the endogenous fluorescence of HSA was static quenching.•Molecular docking and molecular dynamic (MD) simulations verified that myricitrin could be stably combined with HSA.

查看译文

关键词

Myricitrin,Human serum albumin,Spectroscopic methods,Molecular modelling,Antioxidation

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要