Herpes simplex virus-induced murine dry skin model through sweating disturbance

Journal of Dermatological Science(2022)

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摘要
•We established the sweating disturbance/dry skin mouse model by HSV infection.•Hyperthermic stress enhanced sweating disturbance.•HSV-1 DNA was detected in sweat glands and dorsal root ganglia.•Increased anti-HSV-1 IgG prevented sweating disturbance.•Sweating disturbance could be due to HSV-induced dysfunction of sweat glands.
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关键词
Eccrine sweat gland,Herpes simplex virus,Sweat disturbance
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