Florid squamous papilloma of the tongue

A 47-year old Chinese woman presented with a 2-year history of multiple small flammulated papilloma-liked lesions on her tongue. She has noted an increase of the size and number of lesions within the past month, with significant harsh feeling, but the taste sensation is normal. The physical examination showed diffusely multiple, florid, and slight raised spots in different sizes, measuring from 1 to 3 mm in dimensions, appearing on the dorsal surface and lateral borders of the tongue (Figure 1A and 1B). Incisional biopsy of the lesion area showed papillary mucosal epithelial, dermal superficial collagen bundle and mucous matrix hyperplasia (Figure 1C). She denied any other cutaneous or systemic abnormalities. Based on histopathological examination, a diagnosis of squamous papilloma was made.