Utility of PSA density in patients with PI-RADS 3 lesions across a large multi-institutional collaborative

Johnathan Drevik,Zafardjan Dalimov,Robert Uzzo,John Danella,Thomas Guzzo, Lawrence Belkoff,Jay Raman,Jeffrey Tomaszewski,Edouard Trabulsi,Adam Reese,Eric A. Singer,Kaynaat Syed,Bruce Jacobs,Andres Correa,Marc Smaldone,Serge Ginzburg

Urologic Oncology: Seminars and Original Investigations（2022）

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摘要

•Solitary PIRADS 3 lesions with low PSA density have an 86% NPV for clinically significant PCa on subsequent prostate biopsy.•Overall Incidence of clinically significant prostate cancer in PIRADS 3 lesions is 20%.•When PSA density is < 0.15, only 14% of men with a PIRADS 3 lesion harbor clinically significant PCa on prostate biopsy.

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关键词

Prostate cancer,PSA density,PIRADs 3,MRI,Prostate cancer screening

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