Prospective Optimization of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Lymph Node Assessment for Lung Cancer: Three Needle Agitations Are Noninferior to 10 Agitations for Adequate Tumor Cell and DNA Yield

David Fielding,Andrew J Dalley,Mahendra Singh,Lakshmy Nandakumar,Katia Nones,Vanessa Lakis,Haarika Chittoory,Kaltin Ferguson,Farzad Bashirzadeh,Michael Bint,Carl Pahoff, Jung Hwa Son,Alan Hodgson,Sowmya Sharma,David Godbolt, Kylie Coleman, Lenore Whitfield,Nicola Waddell,Sunil R Lakhani,Gunter Hartel,Peter T Simpson

JTO Clinical and Research Reports（2022）

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摘要

Three agitations are noninferior to 10 agitations for overall abundance of malignant cells and DNA content on smears. A smear with adequate DNA for panel sequencing could almost always be made with the first needle pass using three agitations.

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关键词

Cytology smears,Molecular testing,Lung cancer,EBUS TBNA

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