Hypercalcaemia and acute kidney injury: A rare presentation of seminoma

Etienne Paris, Claire Fugaccia,David Hendry,Mark Findlay,Jeff White

JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH(2022)

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摘要
Hypercalcaemia is common in patients with malignancy, but is rare in seminoma with only eight cases reported in the literature. We present an unusual case of a 36-year-old man who presented with hypercalcaemia and stage 3 acute kidney injury. He presented initially with headache and malaise, and was found to have markedly deranged blood tests. He underwent a renal biopsy before imaging confirmed an unexpected large abdominal mass, which was confirmed histologically to be a seminoma. He was referred to a tertiary oncology centre, and underwent emergency chemotherapy and radical resection with no evidence of recurrence to this date and with return to normocalcaemia.
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关键词
seminoma, hypercalcaemia, acute kidney injury, parathyroid hormone related peptide
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