Early hyperdopaminergic state following sub-thalamic nucleus deep brain stimulation in Parkinson disease

F. Lamy,O. Lagha-Boukbiza,T. Wirth, C. Philipps, N. Longato, O. Gebus, S. Montaut, A. Mengin, J. Voirin, F. Proust, N. Tuzin, M. Anheim,C. Tranchant

Revue Neurologique（2022）

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摘要

We found that early PoOHS are frequent in PD after STN-DBS, mostly de novo, with ICBs and hypomania being the most frequent. Despite a good prognosis of PoOHS at one year, our work emphasizes the importance of both a cautious adjustment of dopamine agonist doses and a close non-motor monitoring pre- and post-STN-DBS in PD.

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关键词

Early hyperdopaminergic state,Impulse control behavior,Impulse control disorder,Deep brain stimulation,Hypomania,Psychotic disorder

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