Amanitin intoxication: effects of therapies on clinical outcomes - a review of 40 years of reported cases.
Clinical toxicology (Philadelphia, Pa.)(2022)
摘要
Based on data available, no statistical differences could be observed for the effects of NAC, PEN or SIL in proven poisonings with amanitin-containing mushrooms. However, monotherapy with SIL or PEN and combination therapy with NAC/SIL appear to be associated with higher survival rates compared to supportive care alone. AST, ALT, TSB, and INR values are possible predictors of potentially fatal outcomes.
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关键词
Amatoxin,N-acetylcysteine,benzylpenicillin,silibinin,systematic review
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