Long-term glycemic variability and risk of adverse health outcomes in patients with diabetes: A systematic review and meta-analysis of cohort studies

Junxiang Chen,Qian Yi, Yuxiang Wang,Jingyi Wang,Hancheng Yu, Jijuan Zhang,Mengyan Hu, Jiajing Xu, Zixuan Wu,Leying Hou,Zhe Zhang,Yanbo Zhang,Yi Wang,Zhouzheng Tu,Kun Yang,Kunquan Guo,Yanfeng Zhou,Tingting Geng,Xiongfei Pan,Gang Liu,Peige Song,An Pan

Diabetes Research and Clinical Practice（2022）

引用 18|浏览6

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摘要

•A meta-analysis including 75 articles with 2,051,701 diabetes about long-term glycaemic variability.•Higher HbA1c variability was associated with higher risk of mortality, CVD, renal disease, and peripheral neuropathy.•Higher FPG variability was associated with higher risk of mortality, renal disease, and retinopathy.•Data about associations of glycaemic variability with dementia and cancer were limited.

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关键词

Diabetes mellitus,Glycemic variability,Vascular complications,Death,Meta-analysis

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