Self-reported cognitive impairments and quality of life in patients with gastrointestinal stromal tumor: Results of a multinational survey.

Robert J Ferguson,Jessica Manculich,Hsuan Chang, Nikita J Sareen,Beth E Snitz,Lauren Terhorst,Dana H Bovbjerg,Anette U Duensing

Cancer（2022）

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摘要

A majority of GIST patients report cognitive symptoms that have a negative impact on quality of life, with longer term survivors (≥5 years) tending to report more cognitive impairments. Given the success of TKI therapy to substantially increase overall survival of patients with GIST, addressing CRCI in clinical practice may improve long-term GIST survivor function and quality of life.

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关键词

cancer-related cognitive impairment,gastrointestinal stromal tumor (GIST),neurocognitive outcomes,quality of life,tyrosine kinase inhibitor therapy

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