Strain-to-strain variability among Staphylococcus aureus causing prosthetic joint infection drives heterogeneity in response to levofloxacin and rifampicin.

María Ángeles Meléndez-Carmona,Mikel Mancheño-Losa,Albert Ruiz-Sorribas,Irene Muñoz-Gallego,Esther Viedma,Fernando Chaves,Françoise Van Bambeke,Jaime Lora-Tamayo

The Journal of antimicrobial chemotherapy（2022）

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摘要

Significant variability may be expected in response to levofloxacin and rifampicin among biofilm-embedded S. aureus. A response in the lower range, together with other factors of bad prognosis, could be responsible of treatment failure.

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