ABCL-227 Integral Transformation Index Indicating the Probability of High-Grade B-Cell Lymphoma Development From Transformed Low-Grade Lymphoma

Anna Misyurina,Sergey Kravchenko,Aminat Magomedova,Alla Kovrigina,Tatiana Obukhova,Ksenia Sychevskaya,Vsevolod Misyurin,Fatima Babaeva

Clinical Lymphoma Myeloma and Leukemia（2022）

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摘要

ITI distinguishes cases of tLGLs among HGBLs. c-MYC/BCL2 HGBL DH and HGBL TH are frequently presented by GCB-lymphomas transformed from FL. c-MYC/BCL6 HGBL DH and HGBL NOS can develop from MZL with paraprotein secretion. Involvement of the CNS is characteristic of tLGLs.

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关键词

ABCL,high-grade B-cell lymphoma,low-grade lymphoma,transformation,central nervous system,paraprotein secretion

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