Fragment-based design of α-cyanoacrylates and α-cyanoacrylamides targeting Dengue and Zika NS2B/NS3 proteases

Gabriel Gomes Vilela,Wadja Feitosa dos Santos Silva, Vitoria de Melo Batista,Leandro Rocha Silva,Hannah Maus,Stefan Josef Josef Hammerschmidt,Clara Andrezza Crisóstomo Bezerra Costa, Orlando Francisco da Silva Moura,Johnnatan Freitas,Grazielle Lobo Coelho, Júlia de Andrade Brandão,Leticia Anderson,Ênio José Bassi,João Araújo-Júnior,Tanja Schirmeister,Edeildo Ferreira da Silva-Júnior

New Journal of Chemistry（2022）

引用 3|浏览8

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摘要

Viruses belonging to the Flaviviridae family account for millions of cases of infections worldwide, mainly Dengue (DENV) and Zika (ZIKV) viruses. Both mosquito-borne flaviviruses are transmitted by bites of infected...

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关键词

zika ns2b/ns3,dengue,fragment-based

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