Reduced emergent character of neural dynamics in patients with a disrupted connectome

Andrea I. Luppi,Pedro A.M. Mediano,Fernando E. Rosas,Judith Allanson,John D. Pickard,Guy B. Williams,Michael M. Craig,Paola Finoia,Alexander R.D. Peattie,Peter Coppola,David K. Menon,Daniel Bor,Emmanuel A. Stamatakis

NeuroImage（2023）

引用 3|浏览32

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摘要

•Relationship between emergent dynamics, functional hierarchy, and controllability.•DOC patients exhibit less hierarchical and emergent neural dynamics.•DOC patients’ structural connectomes exhibit compromised modal controllability.•Whole-brain model based on patient connectomes recapitulates functional alterations.

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关键词

Whole-brain modelling,Network control theory,Hierarchy,Emergence,Information decomposition,Disorders of consciousness

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