Role of human leukocyte antigen in anti-epileptic drugs induced stevens-johnson syndrome/toxic epidermal necrolysis: A meta-analysis

Girish Thunga,Asha K. Rajan,Muhammed Rashid,Manik Chhabra,Viji Chandran,Sreedharan Nair,Ananth Kashyap,Rajesh Venkataraman

Seizure（2022）

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摘要

•HLA polymorphism has a strong association in AED induced SJS/TEN.•Asian population is more prominent to HLA polymorphism when compared to others.•Carbamazepine and phenytoin induced SJS/TEN were high in those with various HLA alleles polymorphism.

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关键词

Human leukocyte antigen,Stevens–Johnson Syndrome,Toxic epidermal necrolysis,Carbamazepine,Phenytoin,Allele,Risk

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