Naringin Inhibits the Proliferation, Migration, Invasion and Epithelial-to-Mesenchymal Transition of Gastric Cancer Cells via the PI3K/AKT Signaling Pathway.

Lin Zhu,Jing Shi,Mingchao Mu,Zilu Chen,Chenye Zhao,Xiaopeng Li,Chao Qu,Changchun Ye,Wei Zhao,Xuejun Sun,Xingjie Wang

Alternative therapies in health and medicine（2023）

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摘要

Naringin can block the cell-cycle, induce cancer cell apoptosis, and inhibit the epithelial mesenchymal transition (EMT) process by inhibiting the PI3K-AKT/Zeb1 pathway in gastric cancer cells. Therefore, naringin can inhibit the development of gastric cancer.

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关键词

gastric cancer cells,pi3k/akt signaling pathway,signaling pathway,cancer cells,epithelial-to-mesenchymal

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