Tu1309: SERUM FIBROBLAST GROWTH FACTOR 21 IS MARKEDLY DECREASED FOLLOWING EXERCISE TRAINING IN PATIENTS WITH BIOPSY PROVEN NONALCOHOLIC STEATOHEPATITIS

Jonathan G. Stine,Scot R. Kimball,Jaclyn E. Welles,Ian Schreibman,Alison J. Faust,Jessica Dahmus,Benjamin Stern,Christopher Soriano,Gloriany Rivas,Breianna L. Hummer,Nathaniel R. Geyer,Vernon M. Chinchilli,Kathryn Schmitz,Christopher Sciamanna,Rohit Loomba

GASTROENTEROLOGY（2022）

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摘要

Serum FGF21 is markedly decreased in response to aerobic exercise training, offering a novel mechanism to explain the observed reduction in liver fat and improvement in serum biomarkers of liver fibrosis in patients with NASH who do exercise.

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关键词

biomarker,cardiorespiratory fitness,fatty liver,nonalcoholic fatty liver disease,physical activity

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