Generation of selenium nanoparticles under γ-Irradiation for optical sensing of Carcinoembryonic antigen

Debashree Das, Shalmali Basu,Santanu Ray,Sudeep Koppayithodi,Bibhas Hazra,Subhajit Bandyopadhyay,Abhijit Saha,Kamalika Sen

Journal of Molecular Liquids（2022）

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摘要

•CEA, biomarker of colorectal cancer, is detected by gamma irradiated selenium nanoparticle with LOD 6.91 pg/mL.•The detection is also done in presence of interfering biomolecules present in serum like dextrose, cholesterol, bilirubin.•The interaction between CEA and SeNP-γ was established with fluorescence, CD and theoretical simulations.

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关键词

Selenium nanoparticles,Carcinoembryonic antigen, cancer biomarker,γ-Irradiation,Biosensing

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