Protective effect of 5-heptadecylresorcinol against obesity-associated skeletal muscle dysfunction by modulating mitochondrial biogenesis via the activation of SIRT3/PGC-1α signaling pathway

Ziyuan Wang,Qing Li,Yiming Hao,Zongwei Wang,Haihong Yang,Jie Liu,Jing Wang

Journal of Functional Foods（2022）

引用 6|浏览4

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摘要

•5-heptadecylresorcinol (AR-C17) improves muscle dysfunction.•AR-C17 enhances mitochondrial content and mitochondrial biosynthesis.•AR-C17 improves obesity-induced muscle dysfunction via modulation of SIRT3/PGC-1α signaling pathway.•AR-C17 can be used as functional food ingredient to regulate obesity-associated muscle metabolic diseases.

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关键词

5-heptadecylresorcinol,Obesity,Skeletal muscle,Mitochondrial biogenesis,SIRT3/PGC-1α signaling

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