Evaluation of Plasma Assisted Noninvasive Surgery (PANIS) as a New Approach for the Treating Bullae in Pseudophakic Bullous Keratopathy (PBK); A Clinical Case Report

Purpose: Pseudophakic bullous keratopathy (PBK) is one of the unintended side effects of intraocular surgeries and traumas. This study aims to evaluate plasma as a noninvasive procedure for PBK diseases through drainage of painful and annoying bullae. Methods: Three eyes of three patients with no vision potential were included in this study. Plasma spots are applied on bullae to empty the fluid inside, and also to attach the top of the bullae to the bottom. We evaluated Pain scores, tearing, and burning sensations (scale of 0 to 10) before treatment and one week, one month, and six months after treatment. Results: The results showed that all the annoying bullae entirely eliminated in all patients. No complications and recurrence were observed during the operation and one week, one month, and six months after the procedure. After treatment, there was no tearing and burning sensation. All of the patients scored ten for pain before treatment and zero after treatment. There were no changes in the vision of the patients after treatment. Conclusions: Based on the results, the PANIS method can be used as a safe method for eliminating bullae which are not a good candidate for vision amelioration treatment. This method is safe, quick, office base and inexpensive, which can decrease pain in these patients.