Molecular analysis and favorable clinical outcomes in real-world patients with metastatic renal cell carcinoma.

Frede Donskov,Cathy Anne Pinto,Raluca Predoiu,Claire Fox,Jeanette Baehr Georgsen, Katrine Skaarup,Mehmet Burcu,Rodolfo Perini,Torben Steiniche

Acta oncologica (Stockholm, Sweden)（2022）

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摘要

Data pointed at PD-L1 IHC and angiogenesis expression in ccRCC and hypoxia, glycolysis, and angiogenesis expression in nccRCC as potential prognostic factors. These findings may have implications for the design and interpretation of advanced RCC trials and to identify potential targets for combination therapy strategies.

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关键词

Molecular correlates,clinical benefit,renal cell carcinoma,targeted therapy

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