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Outcomes After Nonresponse and Relapse Post-Tisagenlecleucel in Children, Adolescents, and Young Adults With B-Cell Acute Lymphoblastic Leukemia.

Liora M Schultz,Anne Eaton,Christina Baggott,Jenna Rossoff,Snehit Prabhu,Amy K Keating,Christa Krupski,Holly Pacenta, Christine L Philips,Julie-An Talano,Amy Moskop,Susanne H C Baumeister,Gary Douglas Myers,Nicole A Karras,Patrick A Brown,Muna Qayed,Michelle Hermiston,Prakash Satwani,Rachel Wilcox,Cara A Rabik,Vanessa A Fabrizio,Vasant Chinnabhandar,Michael Kunicki,Sharon Mavroukakis,Emily Egeler,Yimei Li,Crystal L Mackall,Kevin J Curran,Michael R Verneris,Theodore W Laetsch,Heather Stefanski

Journal of clinical oncology : official journal of the American Society of Clinical Oncology（2023）

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摘要
We describe poor survival across patients experiencing nonresponse to tisagenlecleucel. In the post-tisagenlecleucel relapse setting, patients can be salvaged; however, CD19- relapse is distinctly associated with decreased survival outcomes.
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关键词
acute lymphoblastic leukemia,post-tisagenlecleucel,b-cell
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