Study on Integrated Pharmacokinetics of the Component-Based Chinese Medicine of Ginkgo biloba Leaves Based on Nanocrystalline Solid Dispersion Technology.

Hongbao Liang,Chenghong Sun,Zhong Feng,Xianzhen Wang, Lingpeng Kong, Feng Zhu,Jingchun Yao,Xiaomei Yuan,Zhong Liu,Guimin Zhang,Feng Li

International journal of nanomedicine（2022）

引用 2|浏览12

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摘要

This study demonstrated that novel GBCCM NC-SD was prepared using Polyvinylpyrrolidone K30 (PVP K30) and Sodium dodecyl sulfate (SDS) as a synergetic stabilizer and also provided a feasible way to improve the dissolution and oral bioavailability of poorly soluble candidate antihypertensive drugs.

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关键词

Ginkgo biloba,charged aerosol detector,flavonoid aglycones,integrated pharmacokinetics,nanocrystalline solid dispersion,terpenoid lactones

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