Decellularized tympanic membrane scaffold with bone marrow mesenchymal stem cells for repairing tympanic membrane perforation.

Yanqing Lu,Jingzhi Li,Nan Hou,Li Zhou, Xiaoxuan Quan,Ying Tang,Xiaoming Luo,Shi Huang,Ruina Ma

Artificial organs（2022）

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摘要

The synthetic ECM scaffold provides temporary physical support for the three-dimensional growth of cells during the tissue developmental stage. The scaffold stimulates cells to secrete their own ECM required for tissue regeneration. The recellularized TM patch shows potential as a natural, ultrastructure biological material for TM reconstruction.

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关键词

bone marrow mesenchymal stem cell,decellularization,extracellular matrix,tissue engineering,tympanic membrane

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