Sputum cell‐free DNA for detection of alterations of multiple driver genes in lung adenocarcinoma
Cancer Cytopathology(2022)
摘要
This study demonstrated that sputum cfDNA were successfully used for the detection of multiple driver genes by NGS. Sputum cfDNA could be a valuable surrogate clinical sample for all-in-one test of mutations to guide target therapies, especially for patients with advanced LAC and malignant sputum.
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关键词
NGS,cell-free DNA,driver genes,lung adenocarcinoma,mutations,sputum
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