Magnetic resonance imaging Locus Coeruleus abnormality in amnestic Mild Cognitive Impairment is associated with future progression to dementia.

European journal of neurology(2023)

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摘要
Our findings highlight a potential role of LC-MRI for predicting clinical progression in Mild Cognitive Impairment and support the key role of LC degeneration in the Alzheimer clinical continuum.
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关键词
Alzheimer's disease,Locus Coeruleus,Magnetic Resonance Imaging,Mild Cognitive Impairment,noradrenaline
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