Determining the Relationship Between Blood Pressure, Kidney Function, and Chronic Kidney Disease: Insights From Genetic Epidemiology.

Natalie Staplin,William G Herrington,Federico Murgia,Maysson Ibrahim,Katherine R Bull,Parminder K Judge,Sarah Y A Ng,Michael Turner,Doreen Zhu,Jonathan Emberson,Martin J Landray,Colin Baigent,Richard Haynes,Jemma C Hopewell

Hypertension (Dallas, Tex. : 1979)（2022）

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摘要

In this general population, genetic epidemiological evidence supports a causal role of life-long differences in BP for decreased kidney function, glomerular hyperfiltration, and albuminuria. Physiological autoregulation may not afford complete renal protection against the moderate BP elevations.

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关键词

blood pressure,chronic,creatinine,epidemiology,renal insufficiency

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