Citrullinated fibrinogen forms densely packed clots with decreased permeability

Imre Varjú,Erzsébet Tóth,Ádám Z. Farkas, Veronika J. Farkas,Erzsébet Komorowicz,Tímea Feller,Balázs Kiss,Miklós Z. Kellermayer,László Szabó,András Wacha,Attila Bóta,Colin Longstaff,Krasimir Kolev

Journal of Thrombosis and Haemostasis（2022）

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摘要

The current observations of thin fibers combined with dense packing and low porosity in the presence of citFg can provide a structural framework for the mechanical fragility and lytic resistance of citrullinated fibrin.

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关键词

atomic force microscopy,citrullination,fibrin,protein–arginine deiminases,small‐angle X‐ray scattering

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