Patlak plot based on the first 30 minutes post-injection dynamic 18 F-florbetaben positron emission tomography scan separates amyloid-β positive from negative studies.

This work shows, for the first time, that early (0-30 min post-injection) F-florbetaben dynamic PET scans with reference region-based Patlak plot method could replace the dual acquisition protocol and the 90-110 min standard acquisition.