Cortical atrophy distinguishes idiopathic normal-pressure hydrocephalus from progressive supranuclear palsy: A machine learning approach

•iNPH patients showed reduced thickness and volume in several cortical regions.•iNPH and PSP patients had distinct patterns of cortical involvement.•The volume of the cingulate cortex was globally reduced in iNPH and normal in PSP.•iNPH patients had thickening in the superior parietal gyrus compared to controls.•A machine learning model using cortical data accurately distinguished iNPH from PSP.