Decreased expression of ADAM10 on monocytes is associated with chronic allograft dysfunction in kidney transplant recipients.

Yamei Li,Yangjuan Bai, Hua Zhang,Yi Li,Lin Yan,Xueqiao Wang,Jiwen Fan,Yunfei An,Zhengli Wan,Shumeng Hu,Lanlan Wang,Yunying Shi

International immunopharmacology（2022）

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摘要

Our data indicated that ADAM10, especially its decreased expression on monocytes, may play an important role in the progression of CAD in KTRs. However, whether there is an interaction between ADAM10 and mTim-3 in the pathogenesis of CAD in KTRs needs to be further studied.

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关键词

ADAM10,ADAM17,Chronic allograft dysfunction,Kidney transplantation,Tim-3

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