Correction to: Specific Antibodies to the Fragments of Meningococcal IgA1 Protease during the Formation of Immunity to Bacterial Infections

O. V. Kotel’nikova,Yu. A. Prokopenko, A. A. Zinchenko, O. A. Razgulyaeva, E. A. Nokel’,D. M. Karlinsky,L. S. Zhigis, L. D. Rumsh

Bulletin of Experimental Biology and Medicine(2022)

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摘要
The features of individual fragments of IgA1 protease of Neisseria meningitidis serogroup B during the formation of immunity to bacterial infections in animals and humans were studied. The antibodies to the immunogenic regions of the studied proteins are also detected in mice infected with some bacterial pathogens and in humans with bacterial meningitis. A region of IgA1 protease was identified that is not capable of producing antibodies during immunization of animals, but that detects homologous antibodies in the blood of humans and animals recovered from bacterial infections. It has been suggested that this fragment plays a regulatory role in the process of immunogenesis.
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关键词
IgA1 protease, recombinant proteins, immunogenicity, bacterial infections
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