Wnt5a-Ror2 signaling mediates root resorption

Xinyi Li,Shushu He,Xiaoge Jiang,Jingchen Xu,Yao Lin,Jialiang Zhou,Ziyu Li,Song Chen

American Journal of Orthodontics and Dentofacial Orthopedics（2022）

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摘要

•Wnt5a-Ror2 signaling in PDLCs enhanced by excessive force could promote RANKL release and induce odontoclast differentiation.•Wnt5a-Ror2 signaling may play an important part in the onset of external root resorption.•The less resorption of the immature tooth may be due to odontoclastogenesis inhibition by decreased Wnt5a-Ror2 signaling.

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mediates root resorption,a-ror

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