Prenatal exposure to ambient air pollution is associated with early life immune perturbations

Casper-Emil Tingskov Pedersen,Anders Ulrik Eliasen,Matthias Ketzel,Jørgen Brandt,Steffen Loft,Lise Marie Frohn,Jibran Khan,Susanne Brix,Morten A Rasmussen,Jakob Stokholm,Bo Chawes,Andreanne Morin,Carole Ober,Hans Bisgaard,Marie Pedersen,Klaus Bønnelykke

The Journal of allergy and clinical immunology（2023）

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摘要

Prenatal exposure to ambient air pollution was associated with early life immune perturbations conferring risk of allergic rhinitis and asthma. These findings suggest potential mechanisms of prenatal exposure to ambient air pollution on the developing immune system.

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关键词

Air pollution,asthma,allergy,childhood,environment,epigenetic,inflammation,immune,sensitization,traffic,urbanization

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