Statistical breathing curve sampling to quantify interplay effects of moving lung tumors in a 4D Monte Carlo dose calculation framework

Asmus von Münchow,Katrin Straub,Christoph Losert,Roel Shpani,Jan Hofmaier,Philipp Freislederer,Christian Heinz,Christian Thieke,Matthias Söhn,Markus Alber,Ralf Floca,Claus Belka,Katia Parodi,Michael Reiner,Florian Kamp

Physica Medica（2022）

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摘要

•4D Monte Carlo dose calculation and accumulation tool to quantify interplay effects.•Statistical sampling of the breathing curve is introduced to broaden applicability.•Possibility to comprehensively assess and evaluate dosimetric interplay effects.•Linac-log file based recalculations and DICOM-RT plan based prospective simulations.

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关键词

4D dose calculation,Lung tumors,Monte Carlo dose calculation,Interplay effects

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