The Prognostic and Drug-targeting Value of Lymphoid Enhancer-binding Factor-1 in Hepatocellular Carcinoma.

Ruixiang Guo,Huiru Dai, Fuweijian Liu,Minling Liu,Xueying Li,Tingwei Li,Jiehao Liao,Zhe-Sheng Chen,Yuchen Liu,Shuo Fang

Recent patents on anti-cancer drug discovery（2022）

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摘要

LEF1 is a latent prognostic molecular biomarker of HCC. The cell cycle, and WNT and NOTCH signaling pathways are regulated by LEF1 in HCC. LEF1 could be a potential drug target for HCC.

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关键词

Hepatocellular carcinoma,LEF1,NOTCH,WNT,drug target.,oncogene,prognostic biomarker

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