Hemostasis Proteins in Invasive Meningococcal and Nonmeningococcal Infections: A Prospective Multicenter Study.

Nienke N Hagedoorn,Navin P Boeddha,Daniela S Kohlfuerst,Suzanne Anderson,Enitan D Carrol,Paul Agapow,Michiel van der Flier,Jan Hazelzet,Jethro Herberg,Taco Kuijpers,Michael Levin,Federico Martinon-Torres,Angelique van Rijswijk,Luregn J Schlapbach,Clementien Vermont,Werner Zenz,Willem A Dik,Gertjan Driessen,Marieke Emonts

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies（2022）

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摘要

Hemostatic disturbances in childhood bacterial infections are not limited to meningococcal sepsis but occur with a comparable severity across nonmeningococcal infections. High thrombomodulin and high ADAMTS-13 had good discriminative ability for mortality. Our results emphasize the importance of hemostatic disturbances in meningococcal and nonmeningococcal pediatric bacterial infections.

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bacterial infection,children,coagulation,hemostasis proteins,intensive care,mortality

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