An Alternatively Spliced p62 Isoform Confers Resistance to Chemotherapy in Breast Cancer.

Qianying Guo,Hao Wang,Jiahao Duan,Wenwu Luo,Rongrong Zhao, Yuting Shen,Bijun Wang, Siqi Tao,Yi Sun,Qian Ye,Xiaomin Bi,Hui Yuan,Qiang Wu,Peter E Lobie,Tao Zhu,Sheng Tan,Xing Huang,Zhengsheng Wu

Cancer research（2022）

引用 4|浏览16

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摘要

Resistance to NAC in breast cancer is driven by a novel p62 mRNA isoform that escapes miRNA-mediated repression and leads to increased p62 protein expression.

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关键词

p62 isoform confers resistance,chemotherapy,breast cancer

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