Pearls & Oy-sters: Tumefactive Demyelinating Lesions With MOG Antibodies Preceding Late-Infantile Metachromatic Leukodystrophy.
Neurology(2022)
摘要
The development of acute neurological dysfunction associated with tumefactive demyelinating lesions (TDL) and mild diffuse involvement of the corpus callosum has been described in children as a sentinel event that may allow diagnosis of juvenile metachromatic leukodystrophy (MLD) at an early and potentially treatable stage. We report a child that developed this clinico-radiological pattern associated with myelin oligodendrocyte glycoprotein (MOG) antibodies several months prior the onset of progressive symptoms of late infantile MLD.
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关键词
tumefactive demyelinating lesions,antibodies,oy-sters,late-infantile
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