Systemic Disease and the Impact on Esophageal Carcinoma Management: The Big Picture

Impact of Diabetes on Pathologic Response to Multimodality Therapy for Esophageal CancerThe Annals of Thoracic SurgeryPreviewThe incidence of esophageal cancer has increased faster than that of most cancers. Evidence from other malignant neoplasms suggests that diabetic patients have a worse response to multimodality therapy. We hypothesized that diabetic patients with esophageal cancer will have a decreased response to neoadjuvant chemotherapy and radiation therapy compared with nondiabetic patients. Full-Text PDF